Arthroben contains a blend of natural bioflavonoids, which provides comprehensive, balanced inhibition of three metabolic pathways (COX-1, COX-2, 5-LOX) unlike NSAIDs which cause strong, selective inhibition of only one individual inflammatory pathway. This well-balanced method of action helps to minimize systemic side effects, making it gentle on the GI tract while effectively managing the metabolic imbalances of osteoarthritis (OA). Arthroben also features two variations of hydrolyzed collagen which boost anabolic processes in connective tissues and inhibit various catabolic enzymes in order to help stimulate the repair process. This supports an adequate volume of cartilage as well as the elastic properties of connective tissues, exactly what is necessary to maintain healthy joints. Arthroben is categorized as a Medical Food in the US.